迅速减压对血管紧张素转换酶、乳酸脱氢酶及碱性磷酸酶的影响  

Changes in ACE, LDH and AKP in BALF and blood after rapid decompression in rabbits

作　　者：肖华军[1] 刘晓鹏[1] 苏迅[1] 周金立[2] 王洪波[2] 付丽姗[1] 石强[1] 金忠正[1] 秦志峰[1] 王琼[1] 陈娟[1] 

机构地区：[1]北京空军航空医学研究所,100036 [2]空军总医院

出　　处：《解放军医学杂志》2004年第10期845-846,共2页Medical Journal of Chinese People's Liberation Army

基　　金：空军科学研究基金资助课题 (编号kj0 2 2 32 )

摘　　要：目的　探讨迅速减压对兔支气管肺泡灌洗液和血液中血管紧张素转换酶、乳酸脱氢酶及碱性磷酸酶的影响。方法　将 30只新西兰白兔随机分为慢上升减压组和迅速减压组 ,测定兔支气管肺泡灌洗液和血液中的血管紧张素转换酶、乳酸脱氢酶及碱性磷酸酶活性。结果　迅速减压组兔支气管肺泡灌洗液中这 3种酶的活性均有不同程度的升高。结论　这些指标同时升高 ,可以提示发生了迅速减压肺损伤 ,其升高程度与肺受损的程度一致。Objective To study changes in ACE, LDH and AKP in BALF and blood after rapid decompression in rabbits. Methods Thirty healthy New-Zealand rabbits were randomly divided into low decompression group and rapid decompression group. The respective activity of ACE, LDH and AKP in BALF and blood of rabbits was measured. Results Various degrees of increase in activity of ACE, LDH and AKP in BALF were observed after rapid decompression. Conclusion The simultaneous enhancement of activity of these enzymes suggest that there was injury to the lung consistent with the degree of injury after rapid decompression.

关 键 词：迅速减压 支气管肺泡灌洗液 血管紧张素转换酶 乳酸脱氢酶 碱性磷酸酶 

分 类 号：R852.12[医药卫生—航空、航天与航海医学]