永久性叶轮式左心室辅助装置的研究(英文)  

Permanent impeller left ventricular assist device

作　　者：袁海宇[1] 茹伟民[1] 曾培[1] 钱坤喜[1] 

机构地区：[1]江苏大学生物医学工程研究所,江苏省镇江市212013

出　　处：《中国临床康复》2004年第30期6800-6801,i002,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：背景:绝大多数研究者都采用电磁轴承来实现叶轮血泵转子的悬浮,同时会带来一系列新的问题,比如装置的结构和控制更加复杂,消耗控制电能,增加了装置的体积和重量。目的:采用永磁轴承和液膜轴承设计无源磁悬浮心室辅助装置,并与电磁磁悬浮方法设计的心室辅助装置进行比较。方法:装置由径向驱动,仅包含一个定子和一个转子。转子由驱动磁钢和叶轮组成;电机线圈和泵壳组成定子。在装置的两端安装两付永磁轴承,为转子提供轴向悬浮力。同时,通过机械设计方法在血泵内部形成液膜轴承,产生径向的液膜动压力使转子在工作转速条件下能够径向悬浮。结果:装置重200g,直径40mm。转子的位置测量实验表明,当血泵的转子转速超过3250r/min、流量大于1L/min时转子能够悬浮起来;装置的血动力学试验表明,转子转速达到3500～4000r/min时,血泵输出流量可达4～6L/min,压力达到100mmHg,可以满足临床心室辅助的要求。结论:采用永磁轴承和液膜轴承设计永久性心室辅助装置的思路是可行的,装置不仅可以输出符合心室辅助要求的流量和压力,而且装置的设计比电磁磁浮血泵更加简洁、不需要人为控制,而且体积小、质量轻,提高了可植入性。BACKGROUND:Most investigators have used electromagnetic bearings to achieve ro tor levitation of impeller blood pump,which will result in some new problems lik e complicated structure and control, remarkable energy consumption and additiona l volume and weight of the device. OBJECTIVE:To design a permanent impeller left ventricular assist device(LVAD) using permanent magnet bearing and fluid film bearing, and compare with the trad itional electromagnetic levitated devices. METHODS:The device is radially driven and has a stator and a rotor.The rotor c onsists of driven magnets and impeller;and the stator consists of the motor coil and pump housing.Two permanent magnet bearings have been installed to provide a xial levitation for the rotor.And meanwhile,a fluid film bearing has been create d through specific mechanic design to produce sufficient centering force that le ads to radical levitation of the rotor.During working conditions,the rotor can b e disaffiliated from the stator radially. RESULTS:The device weighed 200 g,with the diameter of 40 mm. The detection of rotor position revealed that the precondition of levitation was a rotating speed over 3 250 revolutions per minute and a high flow rate over 1 L per minute;Hemo dynamic test indicated that the device as a LVAD required a rotating speed bet ween 3 500-4 000 revolution per minute for producing a blood flow of 4-6 L per minute against 100 mm Hg pressure, so that it could meet the requirement of cli nical ventricle assist. CONCLUSION:It is feasible to develop a permanent rotary LVAD device with perma nent magnet bearing and blood film bearing.The device can not only meet the clin ical requirement on flow rate and pressure for ventricular assist, but also be m ore concise as compared with electromagnetic levitation blood plump.It is of no artificial control,with simple structure,lower weight and better implantability.

关 键 词：心室辅助装置 叶轮血泵 左心室 血动力学 临床 永久性 方法设计 研究者 要求 结论 

分 类 号：R318[医药卫生—生物医学工程] R654.2[医药卫生—基础医学]