降钙素原在新生儿败血症诊断中的价值  

Procalcitonin for early diagnosis of sepsis in neonates

作　　者：黄玉春[1] 边兴艳[1] 李茹琴[1] 庄兰春[1] 程宪[1] 郑洁[1] 

机构地区：[1]大连市儿童医院,辽宁大连116012

出　　处：《小儿急救医学》2004年第5期292-294,共3页Pediatric Emergency Medicine

摘　　要：目的　为探讨血清降钙素原 (PCT)对新生儿败血症早期诊断及鉴别诊断的价值。方法　采用免疫色谱法对 98例不同程度感染的新生儿进行PCT测定。结果　败血症患儿PCT阳性 (≥0 5ng/ml)率 95 % (其中 75 %≥ 2ng/ml,1例阴性病例为血培养阳性的脓疱疹患儿 ,临床无炎性反应表现 ) ,局部感染阳性率 5 2 6 % ,非感染 7 6 9%。所有上呼吸道感染患儿均阴性。新生儿PCT水平在败血症及其他感染患儿间有显著差异。Objective To investigate procalcitonin(PCT).for early and differential diagnosis of sepsis in neonates.Methods 98 neonates with different severity of infections were detected for PCT by immune chrimatography(PCT-Q).Results PCT was positive(≥0.5?ng/ml)in 95% sepsis cases(75%≥2?ng/ml,the only l negative case was with blood culture positive but without any clinical inflammation signs),and 5.26% in local infection cases,7.69% in uninfection cases,PCT was negative in all the common cold cases.PCT levels were significantly different between sepsis cases and local infection cases or viral infection cases such as upper respiratory infection.Conclusion PCT seems to be a good mark for early and differential diagnosis of neonate sepsis.

关 键 词：降钙素原 败血症 新生儿 感染 

分 类 号：R722.1[医药卫生—儿科]