2003年广州地区淋球菌对抗生素耐药性结果分析  

Analysis of Antibiotic Resistance of Neisseria gonorrhoeae in Guangzhou,2003

作　　者：曹文苓[1] 黎小东[1] 李嘉彦[1] 李平[1] 林路洋[1] 吴德标[1] 

机构地区：[1]广州市皮肤病防治所,广东广州510095

出　　处：《中国微生态学杂志》2004年第5期311-311,313,共2页Chinese Journal of Microecology

摘　　要：目的　了解广州地区淋球菌对抗生素的耐药性及PPNG和TRNG的流行状况。方法　用琼脂稀释法测定最低抑菌浓度 (MIC)以及用纸片碘量法检测 β 内酰胺酶。 结果　 116株淋球菌检出PPNG30株 (2 5 9% )、TRNG36株 (31% )、环丙沙星耐药率达 93 1% ,头孢三嗪、壮观霉素未发现耐药菌株 ,且抗菌活性最强。Objective To survey the antibiotic resistance and the prevalence of PPNG and TRNG in Guangzhou Method Minimum inhibitory concentrations(MIC)to penicillin G,tetracycline,ciprofloxacin,ceftriaxone and spectiomycin were determined using the agar dilution method,and β-lactamase by paper iodin quantitative method.Results 30 strains of Neisseria gonorrhoeae produced β-lactamase.while 36 showed plasmid-mediated,high-level resistance to tetracycline(TRNG).Resistant rates of ciprofloxacin was as much as 93.1%.There was no resistance to ceftriaxone and specitinomycin.The ceftriaxone and specitnomycin activity is stronger.Conclusion The study showed that it is important to successively survey the antibiotic resistance of Neisseriae gonorrhoeae.

关 键 词：淋球菌 结果分析 抗生素耐药性 广州地区 头孢三嗪 琼脂稀释法 最低抑菌浓度(MIC) 耐药菌株 抗菌活性 流行状况 

分 类 号：R378[医药卫生—病原生物学] R759[医药卫生—基础医学]