二硫化碳作业女工受孕时间影响因素的研究  

Study on the factors influencing pregnancy time in women exposed to carbon disulphide

作　　者：李佩贤[1] 王志萍[1] 韩连堂[1] 邱玉刚[1] 侯光萍[2] 任永清[2] 

机构地区：[1]潍坊医学院卫生学教研室,山东潍坊261042 [2]潍坊市人民医院职业病科,261042

出　　处：《中国职业医学》2004年第5期23-25,共3页China Occupational Medicine

摘　　要：目的　探讨二硫化碳影响女工受孕时间的危险因素。方法　前瞻观察欲生育女工妊娠所需的月经周期数 ,采用Cox回归分析方法筛选影响女工受孕时间的危险因素。结果　接触组女工的平均受孕时间中位数为 2 2 5个月 ,对照组女工的平均受孕时间中位数为 1 70个月 ,接触组女工的受孕时间明显延长 (P <0 0 0 1) ;接触组女工的早早孕丢失率 (2 9 5 7% )明显高于对照组的早早孕丢失率 (13 11% ,P <0 0 0 1) ;Cox回归分析提示 ,二硫化碳作业女工受孕时间延长的主要危险因素是女工接触二硫化碳 (P =0 0 0 1,RR =0 3 2 7)和工作紧张 (P =0 0 0 1,RR =0 694)。结论　女工接触二硫化碳和工作紧张可能是导致该行业作业女工受孕时间延长的主要危险因素。Objective To observe the risk factors influencing pregnancy time in women exposed to carbon disulphide(CS 2) Methods A prospective observation on the numbers of menstruation cycles needed for getting pregnancy for each woman who attempted to have a baby Cox regression analysis was used to detect the factors collected in the prospective study Results The median cycles for getting successful pregnancy in the exposed group was 2 25 cycles while 1 70 in the control group The pregnancy time in the exposed group was longer than that in the control ( P <0 001) The probabilities of early pregnancy loss were 29 57% in the exposed group and 13 11% in the control ( P <0 001) It was shown that the main factors what enhanced pregnancy time for women were the exposure of CS 2( P <0 001, RR =0 327) and work at high pressure( P <0 001, RR =0 694). Conclusion It was suggested that CS 2 and intensive working might be the main factors on longer pregnancy time of women.

关 键 词：受孕时间 作业女工 危险因素 二硫化碳 COX回归分析 对照组 工作紧张 研究 接触 筛选 

分 类 号：R135[医药卫生—劳动卫生] R169.42[医药卫生—公共卫生与预防医学]