血浆纤维蛋白原水平对不稳定性心绞痛患者的预后判断价值  

The prognostic value of plasma levels of fibrinogen in unstable angina pectoris

作　　者：陈兆彦[1] 段玉柱[1] 

机构地区：[1]淮南市第一人民医院心内科,安徽淮南232007

出　　处：《中国基层医药》2004年第10期1185-1186,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　探讨血浆纤维蛋白原 (Fibrinogen ,Fib)水平对不稳定性心绞痛 (UAP)患者的预后判断价值。方法　对 80例UAP患者进行血浆Fib测定 ,同时观察住院期间的心脏事件发生率。结果　根据Fib水平将 80例UAP患者分为Fib正常组 (n =33,4 1 2 5 % ,Fib <4 0g/L)和Fib升高组 (n =4 7,5 8 75 % ,Fib≥4 0 g/L)。Fib升高组 30d内发生心脏事件 (急性心肌梗死、心脏性猝死及顽固性心绞痛 )的发生率明显高于Fib正常组 ( 4 8 94 %比 19 8% ,P <0 0 1)。结论　血浆Fib水平与UAP患者心脏事件的发生显著相关 ,对判断UAP患者预后有较好的预测价值。Objective To evaluate the prognostic value of plama fibrinogen(Fib) in unstable angina pectoris(UAP).Methods Plasma fibrinogen was measured in 80 UAP patients.In hospital cardiac events were observed and recorded.Results According to the level of Fib,eighty patients were divided into Fib normal group(n=33,41.25%,Fib<4.0g/L)and Fib elevated group(n=47,58.75%,Fib≥4.0g/L).The incidence of cardiac events,including AMI,sudden cardiac death and refractory angina pectoris within 30 days,were significantly higher in Fib elevated group than in Fib normal group(48.94% vs 19.8%,P<0.01).Conclusion Plasma fibrinogen level is associated with the incidence of cardiac events in patients with UAP and could predict the prognosis of patients with unstable angina.

关 键 词：患者 UAP 心脏事件 血浆纤维蛋白原 预后判断 不稳定性心绞痛 正常 水平 结论 目的 

分 类 号：R541.4[医药卫生—心血管疾病]