老年前期和老年期糖尿病Ⅱ型患者骨密度的变化与中医辨证的关系  

Bone mineral density in senile and senescent patients with diabetes mellitus and its relationship with differentiation of symptoms according to traditional Chinese medicine

作　　者：张洪[1] 魏之玉[1] 霍青[1] 程益春[1] 

机构地区：[1]济南山东中医药大学附属医院老年病科

出　　处：《中国骨质疏松杂志》1997年第4期30-32,共3页Chinese Journal of Osteoporosis

摘　　要：为了观察老年前期、老年期糖尿病（ＮＩＤＤＭ）患者的骨代谢变化以及与中医辨证分证的内在联系，我们采用单光子骨密度仪对老年前期和老年期ＮＩＤＤＭ患者６６例及正常对照组５９例进行骨密度测量比较，同时对ＮＩＤＤＭ患者进行辨证分证并测定空腹血糖、血钙、血磷、血ＡＫＰ组间对照。结果提示：（１）ＮＩＤＤＭ组无论男性或女性骨密度（ＢＭＤ）均明显降低（ＰＭＯ．０５），说明糖尿病患者与正常人比较，其“肾虚”和衰老的程度表现的重，进程出现的早。（２）糖尿病患者各辨证分证组间，其骨密度变化无显著性差异（Ｐ＞０．０５），说明糖尿病性骨密度降低，除与中医“肾虚”有关外，与其他脏腑功能的改变及气血运行状况均有关联。（３）糖尿病患者各辨证分证组间，其血糖、血钙、血磷、血ＡＫＰ的组间比较无显著性差异（Ｐ＞０．０５），说明老年前期和老年期ＮＩＤＤＭ患者的一般血生化代谢指标变化不敏感，中医辨证分证与骨代谢生化指标间无特殊关联。In order to study the bone mineral density (BMD) in senile and senescent patients with diabetes mellitus (NIDDM)and the relationship between BMD and differentiation of symptoms according to traditional Chinese medicine,a comparison was made between 66 patients with NIDDM and 59 healthy volunteers. BMD was measured by single photon bone densitometry; fasting blood sugar,serum calcium,phosphorus and AKP were examineds and differentiation of symptoms according to traditional Chinese medicine was conducted for each patient. The results are as follows: (1)BMD in the patients with NIDDM are all evidently lower than those in healthy persons,no matter men or women,indicating that asthenia of kidney and extent of aging in the diabetic patients are more serious and earlier. (2)For BMD in the patients,there is no difference among different groups of patients with differentiated symptoms, suggesting that the reduction of BMD in the patients is related to the states of other viscera,qi and blood as well as asthenia of kidney. (3 )For blood sugar,serum calcium, phosphorus and AKP in the diabetic patients,there is no difference among different groups with differentiated symptoms,manifesting that differentiation of symptoms does not relate to the changes of blood sugar,serum calcium,phosphorus and AKP.

关 键 词：糖尿病患者 老年前期 NIDDM 老年期 骨密度 中医辨证 糖尿病 血磷 血钙 肾虚 

分 类 号：R587[医药卫生—内分泌] R681[医药卫生—内科学]