老年心力衰竭患者血脑钠肽水平与心功能的关系  

Correlative relationship between level of brain/b-type natriuretic peptide and left ventricular function in old patients with congestive heart failure

作　　者：任节[1] 段宝祥[2] 毛建华[1] 陈爱华[1] 刘永宁[1] 杨惠娟[1] 

机构地区：[1]安徽马鞍山市马钢医院,安徽马鞍山243000 [2]南京医科大学附属南京市第一人民医院心内科

出　　处：《心血管康复医学杂志》2004年第5期421-422,420,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:研究老年心力衰竭患者血脑钠肽(BNP)水平与心力衰竭严重程度、左室功能等的关系。方法:采用ELISA法测定79例老年心力衰竭患者BNNP水平,用心脏彩色多普勒超声诊断仪测定其左室功能。结果:BNP水平随着心功能纽约分级(NYHA)程度的加重而显著增加,其与左室射血分数(LVEF)呈负相关(P<0.05)。结论:老年心力衰竭患者血BNP水平随着心力衰竭严重程度的增加而升高,并能较好反映左室功能状态。Objective: To investigate the correlative relationship among the level of brain/b-type natriuretic peptide (BNP) , and the severity of heart failure (HF) , left ventricular function in old patients with heart failure. Methods: BNP levels of 79 patients with heart failure were measured by ELlSA; Colored Doppler echocardiography was performed to measure the left ventricular function. Results: BNP levels increased with increment of NYHA classification, and this was negatively correlated left ventricular ejection fraction (P<0. 05). Conclusion: BNP level increase with the degree of severity of heart failure and can better reflect the left ventricular function.

关 键 词：心力衰竭患者 老年 BNP 脑钠肽 左室功能 心功能 严重程度 彩色多普勒超声诊断仪 LVEF ELISA法 

分 类 号：R541[医药卫生—心血管疾病] R654.2[医药卫生—内科学]