选择性子宫动脉栓塞治疗子宫腺肌病的临床研究  

Selective uterine artery embolization for the treatment of adenomyosis

作　　者：赵锡立[1] 李俊勇[2] 王志学[1] 周青[1] 段慧[1] 高泽玲[1] 

机构地区：[1]河南大学第一附属医院放射科,河南475001 [2]河南大学医学院,475000

出　　处：《放射学实践》2004年第10期746-748,共3页Radiologic Practice

摘　　要：目的 :研究选择性子宫动脉栓塞 (UAE)治疗子宫腺肌病的临床效果。方法 :对 2 5例经临床、超声或MRI诊断为子宫腺肌病的患者行UAE。采用Seldinger技术经股动脉穿刺 ,将导管选择性插入双侧子宫动脉 ,经导管注入真丝线段和明胶海绵微粒栓塞 ,阻断异位内膜病灶血供。术后观察月经量、痛经程度及子宫、病灶体积等变化。结果 :所有病例随访 3～ 12个月 (平均 8个月 ) ,临床症状缓解率 96%。月经量均恢复正常。 2 0例患者术后痛经完全消失 ,4例明显缓解 ,1例复发 ;栓塞后 6个月 ,子宫体积平均缩小 48.4% ,14个腺肌瘤体积平均缩小 47.1% ;超声检查子宫肌层及病灶内血流信号明显减少。无严重并发症发生。结论 :UAE治疗子宫腺肌病是一种安全、近期疗效显著的方法 ,远期疗效尚需进一步观察。Objective:To assess the clinical effects of selective uterine artery embolization (UAE) in the treatment of adenomyosis.Methods:25 cases with symtomatic adenomyosis were treated by selective UAE.Fragments of silk and gelfoam were introduced through catheter to occlude the blood supply of adenomyosis.After treatment the symptoms and uterine volume of all patients were investigated.Results:All cases were followed up for 3 to 12 months (mean 8 months) after the treatment.All clinical symptoms of 25 patients were relieved.The menorrhagia returned to normal.Dysmenorrhea completely disappeared in 20 patients and significantly alleviated in 4 patients,but reocurred in 1 case.The size of uterus and tumors decreased significantly.The signal of blood flow within the uterus and lesion decreased after UAE.No severe complications were observed in all 25 cases.Conclusion:Selective uterine artery embolization is effective and safe in the treatment of adenomyosis.Further investigation would be required to assess its long-term effect.

关 键 词：子宫内膜异住症 放射学 介入性 栓塞 

分 类 号：R711.74[医药卫生—妇产科学]