1,1’-联-2-萘酚拆分工艺研究  

The Technical Research about the Resolution of Racemic 1,1’-Bi-2-naphthol

作　　者：尹洁[1] 商海霞[1] 施小新[1] 

机构地区：[1]华东理工大学化学与制药学院,上海200237

出　　处：《精细化工中间体》2004年第5期19-20,共2页Fine Chemical Intermediates

摘　　要：研究了用手性苯乙胺和硼酸拆分消旋联萘酚,当消旋联萘酚与手性苯乙胺之比为1∶1.5(mol)、拆分时间为12h时,可以得到收率为44%、光学收率高于99%的手性联萘酚。Resolution of the Racemic 1,1’-bi-2-naphthol was achieved to obtain enantiomerically enriched compound using (R)-(+)-α-Methylbenzylamine and Boric Acid, and gives a yield of 44% and >99% ee when the ratio of Methylbenzylamine to naphthol is 1.5 and the time of the resolution is 12h.

关 键 词：联萘酚 R-(+)-α-苯乙胺 硼酸 拆分 

分 类 号：TQ243.1[化学工程—有机化工]