2,3-二氯苯甲腈的合成研究  

The Synthesis of 2,3-Dichlorobenzonitrile

作　　者：邓洪[1] 廖齐[1] 周莹[1] 

机构地区：[1]中南林学院化学教研室,湖南株洲412006

出　　处：《精细化工中间体》2004年第5期23-24,共2页Fine Chemical Intermediates

基　　金：中南林学院引进高层次人才科研基金资助项目(0113)

摘　　要：以2,3-二氯苯胺开始,经重氮化、Sandmeyer反应得到2,3-二氯苯甲腈,收率达60%以上。国内外尚未见其合成报道。2,3-Dichlorobenzonitrile is the important intermediate for synthesizing 2,3-dichlorobenzoic acid which is the key intermediate for synthesizing3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine ,the new and specific antiepileptic called Lamotigine. Synthesis of 2,3-dichlorobenzonitrilehas not been reported at abroad andhome. 2,3-Dichlorobenzonitrile was synthesized from 2,3-dichloroaniline by diazo and Sandmeyer reaction in 60% upwards yield in the paper.

关 键 词：2 3-二氯苯甲腈 拉莫三嗪 中间体 合成 

分 类 号：TQ242.1[化学工程—有机化工]