老年冠心病伴抑郁症的临床特征及相关因素研究  

Clinical features and correlative factors of senile coronary heart disease accompanied with depression

作　　者：梁积英[1] 胡才友[1] 潘文晶[1] 吕泽平[1] 段小嬿[1] 史文[1] 苏卫红[1] 阳初玉[1] 杨秀塔[1] 

机构地区：[1]广西壮族自治区江滨医院,广西南宁市530021

出　　处：《中国康复理论与实践》2004年第10期616-617,共2页Chinese Journal of Rehabilitation Theory and Practice

基　　金：卫生部保健局资助课题:合同号 (桂CO36)

摘　　要：目的探讨老年冠心病伴抑郁症的临床特点、相关因素及预后。方法选择老年冠心病伴抑郁症患者 5 2例为观察组 ,老年冠心病不伴有抑郁症患者 60例为对照组。对两组患者的临床特点、家庭及社会支持 ,以及Holter监测结果等进行对比分析并随访。结果观察组患者的严重睡眠障碍、焦虑激越、情绪低落、兴趣减退、自觉无用负罪感等症状的发生率与对照组有显著性差异。对照组患者的家庭和睦及社会支持率明显高于观察组。Holter监测显示 ,观察组患者室性心律失常、房性心律失常以及缺血性ST T改变的发生率明显高于对照组 (P <0 .0 5 ,P <0 .0 1)。观察组患者心源性猝死的发生率高于对照组 (P <0 .0 5 )。结论老年冠心病伴抑郁症患者易产生严重睡眠障碍、焦虑激越、情绪低落等症状 ;抑郁症患者心源性猝死率增高 ;ObjectiveTo investigate clinical features, correlative factors and prognosis of senile coronary heart disease accompanied with depression.MethodsFifty two senile patients of coronary hart disease with depression were selected for the observation group, sixty cases without depression as control group. Clinical features, family conditions, society factors and Holter report (supervision) of two groups were analyzed.ResultsClinical features such as severe dyssomnia, anxiety agitation, emotion depressing, loss of interest, feeling waste and sense of guilty in patients of observation group were significant different with those in control group. The rate of family harmoniousness and society supporting between patients of two groups were significantly different. The incidence of ventricular arrhythmias, atrial arrhythmia and myocardial ischemia changes on ST T in the Holter reports of patients in observation group were higher than those in control group ( P<0.05 or P<0.01). The incidence of cardiac sudden death of patients in observation group was also higher than patients in control group ( P<0.05).ConclusionClinical symptoms such as severs dyssomnia, anxiety agitation, emotion depressing are easily occurred in senile coronary heart disease patients with depression. Patients with depression have higher incidence of cardiac sudden death, having better relationship and society support are advantageous to prevent and reduce the depression in senile coronary heart disease patients.

关 键 词：老年 冠心病 抑郁症 临床特点 相关因素 

分 类 号：R541.4[医药卫生—心血管疾病] R749.4[医药卫生—内科学]