重型颅脑损伤后脑性盐耗综合征诊治的探讨  

A Study on Cerebral Salt Wasting Syndrome After Serious Cerebral Injury

作　　者：黄波[1] 高添喜[1] 伍爱平[1] 张雪平 雷飞跃 何民 

机构地区：[1]广东省中山市博爱医院神经外科,广东中山528403 [2]湖南省郴州市立医院神经外科

出　　处：《中国医师杂志》2004年第10期1341-1342,共2页Journal of Chinese Physician

摘　　要：目的　探讨重型颅脑损伤病人并发脑性盐耗综合征的病因、发病机制、诊断及治疗。方法　回顾性分析重型颅脑损伤后发生脑性盐耗综合征的 2 6例 ,通过其临床表现及实验室指标明确诊断 ,确定有效的治疗方法。结果　 5例死亡 ,2 1例低血钠恢复正常。结论　低血钠、高尿钠、低血容量、高尿量、血浆心利钠肽和脑利钠肽升高是脑性盐耗综合征的特点 ,补盐、补水治疗安全、有效。Objective To explore the pathogenesis, reason, diagnosis and treatment of cerebral salt wasting syndrome (CSWS) in the patients with serious cerebral injury. Methods The clinical data of 26 cases of CSWS after serious cerebral injury were analyzed retrospectively. Results The diagnosis of CSWS was confirmed by clinical symptoms of the patients and the results of laboratory examinations. After the effective treatment, the low plasma sodium level of 21 patients was corrected, and 5 patients died. Conclusion Hyponatremia,hypernatruria, hypovolemia, the increase of urinary amount and the elevation of plasma ANP and BNP level were main characteristics of CSWS.The supplement of water and salt was safe and effective in the treatment of CSWS.

关 键 词：脑性盐耗综合征 重型颅脑损伤 诊断 治疗 低血钠 实验室指标 低血容量 伤病 结论 特点 

分 类 号：R651.1[医药卫生—外科学]