养血安神片质量标准的研究  

Studies on Quality Control of Yangxueanshen Tablets

作　　者：龙海燕[1] 张嘉乐[1] 

机构地区：[1]湖南省药品检验所,长沙410001

出　　处：《中国药师》2004年第11期852-854,共3页China Pharmacist

摘　　要：目的 :建立养血安神片的质量控制方法。方法 :用薄层色谱法对养血安神片中的仙鹤草、鸡血藤、地黄、首乌藤进行定性鉴别 ;用HPLC法测定该片中的大黄素含量。结果 :薄层色谱中斑点清晰 ,易于识别 ;HPLC法精密度、重复性良好 ,大黄素进样量在 0 .0 5 2 1～ 0 .15 6 3μg内呈线性关系 ,r =0 .9999,平均加样回收率 98.5 8% (n =5 ) ,RSD =0 .82 %。结论 :本法可有效地控制养血安神片的质量。Objective: To establish a method for quality control of Yangxueanshen tablets.Method: Herba agrimoniae,caulis spatholobi,radix rehmanniae, and caulis polygoni multiflori were identified by TLC. The content of emodin in this tablets was determined by HPLC.Result: The spots in the TLC were clear and distingusihed well.The linear range was within 0.0521 0.1563 μg( r = 0.999 9 ),the average recovery was 98.58% ,and RSD was 0.82% .Conclusion: This method can be used for quality control of Yangxueanshen tablets effectionally.

关 键 词：养血安神片 大黄素 HPLC 

分 类 号：R283[医药卫生—中药学] R272[医药卫生—中医学]