桂苓散的利尿作用  

Diuretic Effects of the Gui Ling San

作　　者：吴国土[1] 林建忠[2] 黄自强[2] 

机构地区：[1]福建医科大学基础医学院生理学与病理生理学系,福州350004 [2]福建医科大学基础医学院药学系,福州350004

出　　处：《海峡药学》2004年第5期56-57,共2页Strait Pharmaceutical Journal

摘　　要：目的 　观察桂苓散的利尿作用。 方法 　采用大鼠代谢笼法及家兔的导尿管法 ,大鼠及家兔给予不同剂量的桂苓散溶液 ,灌胃给药 ,收集给药后 60、12 0、180、2 40 min的尿液 ,并测其尿量。结果 　桂苓散溶液于给药后 1～ 3 h大鼠及家兔的尿量增多 ,与对照组比较有明显的利尿作用( P<0 .0 5 )。 结论 　桂苓散具有一定的利尿作用。OBJECTIVE To observe the diuretic effects of the Gui Ling San(GLS).METHODS The method of metabolizable cage and catheterization were used,The rats and rabbits were given various doses of the GLS Intragastrally.Their urine was collected after the drug was given for 60,120,180,240 minute and the urine were measured.RESULTS after solution of the GLS was given for 1～3 hours,the urine of rats and rabbits increased. The solution of the GLS had distinct diuretic effects(P<0.05).CONCLUSION The GLS had diuretic effects.

关 键 词：桂苓散 利尿作用 代谢笼法 导尿管法 

分 类 号：R969[医药卫生—药理学] R282.71[医药卫生—药学]