线栓法制备大鼠局灶性脑缺血模型影响因素的探讨  

Rat model of local cerebral ischemia by using thread method: study of influenced factors

作　　者：胡凌[1] 高培毅[1] 

机构地区：[1]首都医科大学附属北京市天坛医院神经影像中心,北京100050

出　　处：《中国医学影像技术》2004年第10期1624-1626,共3页Chinese Journal of Medical Imaging Technology

摘　　要：缺血性脑血管病研究的开展需要合适的动物模型。颈内动脉内插入尼龙线的方法不用开颅、可再灌注 ,损伤小 ,故适用范围广泛。线栓法大鼠大脑中动脉局灶性缺血模型是研究脑缺血的标准动物模型 ,许多学者在动物的选择、尼龙线的制备、放入方法和深度、并发症等方面对其进行研究。The animal model of local cerebral ischemia in rat is widely used in acute cerebral vascular diseases. The classic method was inserting a nylon thread into the start of cerebral middle artery to occlude the blood. The influenced factors about the choice of rats, the diameter of nylon thread and complications were studied in this article.

关 键 词：脑缺血 线栓法 动物 实验 

分 类 号：R713[医药卫生—妇产科学] Q95-33[医药卫生—临床医学]