Synergism of atenolol and nitrendipine on hemody-namic amelioration and organ protection in hypertensive rats  

作　　者：He-huiXIE Chao-yuMIAO Yuan-yingJIANG Ding-fengSU 

机构地区：[1]DepartmentofPharmacology,SecondMilitaryMedicalUniversity,Shanghai200433,China

出　　处：《Acta Pharmacologica Sinica》2004年第11期1529-1530,共2页中国药理学报（英文版）

摘　　要：AIM: This study was designed to investigate the possible synergism of atenolol and nitrendipine on blood pressure (BP) and blood pressure variability (BPV) reductions, baroreflex sensitivity (BRS) amelioration, and organ protection in hypertensive rats. METHODS:The dose is 20 mg/kg for atenolol, 10 mg/kg for nitrendipine and the combination of these two drugs. In acute study, a single dose was given via a catheter previously

关 键 词：BPV BRS AIM 

分 类 号：R544.1[医药卫生—心血管疾病]