Effects of pravastatin on pulmonary arteries and aorta reactivity in monocrotalin-induced pulmonary hypertension  

作　　者：PGUERARD 0BARTHEZ FGOIRAND LROCHETTE MBARDOU MDUMAS 

机构地区：[1]LaboratoiredePhysiopathologieetPharmacologieCardiovasculairesExpYrimentales,FacultydeMYdecine,UniversitedeBourgogne,BP87900,21079DijonCedex,France

出　　处：《Acta Pharmacologica Sinica》2004年第11期1544-1544,共1页中国药理学报（英文版）

摘　　要：AIM: Vascular injury caused by monocrotalin (MC) can affect endothelial regulation and induces pulmonary hypertension and heart failure. We showed previously that pravastatin prevented the development of MC-induced pulmonary hypertension by improving pulmonary arteries (PA) endothelium dependent vasodilation. The aims of this study were to compare the

分 类 号：R541.5[医药卫生—心血管疾病]