Research for SIPI0856 in receptor-binding of the 5-HT  

作　　者：Wen-xinDONG Jian-qiLI Xiang-lianNI Feng-huaGU Li-yingHUANG Chao-fengHUANG 

机构地区：[1]ShanghaiInstituteofPharmaceuticalIndustry,Shanghai200437,China

出　　处：《Acta Pharmacologica Sinica》2004年第11期1552-1552,共1页中国药理学报（英文版）

摘　　要：AIM: Using the radio ligand-receptor binding assay to study the combined effect of SIPI0856 with 5-HT1 and 5-HT2 receptors,then, to study the bio-effect of SIPI0856 using isolated organ.METHODS: Using [^3H]-5-HT as the specific ligand of 5-HT1 receptor and [^3H]-spiperone as the specific ligand of 5-HT2 receptor to draw the saturation curves of each. On the basis of the membrane protein concentration provided by the saturation test,

分 类 号：R977[医药卫生—药品]