Differential regulation of δ-opioid receptor trafficking after internalization by TIPP and DPDPE  

作　　者：Min-huaHONG Yi-minTAO Xue-junXU Zhi-qiangCHI Jing-genLIU 

机构地区：[1]DepartmentofNeuropharmacology,ShanghaiInstiturofMateriaMedica,ShanghaiInstitutesforBiologicalSciences,ChineseAcademyofSciences,Shanghai201203,China

出　　处：《Acta Pharmacologica Sinica》2004年第11期1562-1563,共2页中国药理学报（英文版）

摘　　要：AIM: To explore the mechanisms underlying the difference between TIPP and DPDPE in desensitization of the δ-opioidreceptors. METHODS: GH3 cells stably expressing HA-tagged δ-opioid receptors were treated with TIPP, DPDPE (1 μmol/L)or morphine (10 μmol/L) for different periods of time in the presence or absence of 50 μmol/L monensin or 10 nmol/L OA.Internalization of δ-opioid receptor was assessed using

分 类 号：R971.2[医药卫生—药品]