老年人原发性干燥综合征的腺外表现  

The clinical features of extra-exocrine glands of primary Sjgren syndrome in elderly patients

作　　者：苏厚恒[1] 马红[1] 李凝[1] 

机构地区：[1]山东省青岛市立医院免疫风湿科,266011

出　　处：《中华老年医学杂志》2004年第10期708-710,共3页Chinese Journal of Geriatrics

摘　　要：目的　探讨老年人原发性干燥综合征 (PSS)的腺外表现特点。　方法　分析 10 6例老年PSS患者腺外表现的临床特点及实验室检查结果 ,并与 12 0例非老年PSS患者进行比较。　结果　老年组 10 6例 ( 10 0 0 % )和非老年组 97例 ( 80 8% )有腺外表现。老年组出现低钾性心律失常、末梢神经炎 (P <0 0 5 )、低钾性肌麻痹、继发性糖尿病、病理性骨折、三叉神经痛、面神经麻痹者明显多于非老年组 (P <0 0 1) ;超敏性血管炎、无菌性尿道刺激综合征者与非老年组差异无显著性 (P >0 0 5 ) ,非侵蚀性关节炎和关节痛者低于非老年组 (P <0 0 1)。　结论　原发性干燥综合征是一系统性疾病 ,患者常以腺外表现为突出特点就诊 ,特别是老年患者 ,因此应加以鉴别 ,以免误诊或漏诊。Objective To study the clinical features of the extra exocrine gland symptoms of primary Sjgren syndrome(PSS) in elderly people. Methods Clinical data of 106 cases of elderly and 120 cases of non elderly PSS were collected and analyzed. Results A total of 203 cases(89 8%, 203/226) manifested symptoms of extra exocrine glands, in which elderly and non elderly groups accounted for 106(100 0%) and 97(80 8%), respectively. The occurrence rates of arrhythma due to hypokalemia, peripheral neuritis(P<0 05), weakness of muscles due to hypokalemia, secondary diabetes mellitus, pathologic fracture, trigeminal neuralgia, facial nerve paralysis(P<0 01) in elderly group were much higher than those of non elderly group; and the rate of non erosive arthritis in elderly group was lower than that of non elderly group(P<0 01). However, there was no significant difference in the occurrence of hypersensitive vasculitis and sterile uropathy between the two groups(P>0 05). Conclusions The common symptoms of PSS in patients, especially the elderly patients, are extra exocrine gland manifestations as the main complaints though the PSS is a systemic disease. These must be differenciated in order to avoid misdiagnosis.

关 键 词：老年人 非老年 原发性干燥综合征 患者 低钾性 PSS 表现 结论 外表 显著性 

分 类 号：R593.2[医药卫生—内科学]