不同年代北京部分职业人群血脂的增龄变化  

Present status of serum lipid levels in Beijing professional populations and its tendency:a collaborative study of seven research and clinical laboratories in Beijing

作　　者：李健斋[1] 王抒[1] 董军[1] 朱立华[2] 李义龙[3] 高德路 田亚平[5] 董磊[6] 杨力[7] 李淑葵[2] 

机构地区：[1]卫生部北京医院卫生部北京老年医学研究所血脂研究室,北京市100730 [2]北京大学附属第一医院 [3]卫生部北京医院检验科,北京市100730 [4]解放军第三Ο五医院检验科 [5]解放军总医院检验科 [6]北京安贞医院 [7]北京同仁医院检验科

出　　处：《中华老年医学杂志》2004年第10期724-728,共5页Chinese Journal of Geriatrics

基　　金：国家十五攻关课题(2 0 0 1BA70 2B0 1)

摘　　要：目的　了解北京人群的血脂现状及血脂异常流行率。　方法　以 310 6 8例政府机关、科教卫生人员为观察对象 ,男女比 6 :4。对受检者作问卷调查、体检及血液化验。血脂指标包括总胆固醇 (TC)、低密度脂蛋白胆固醇 (LDL C)、高密度脂蛋白胆固醇 (HDL C)及甘油三酯 (TG) ,统计血脂的性别差异与增龄变化 ,血脂异常的年龄标化及不同性别与年龄组的流行率。　结果　与 80年代资料相比 ,TC、LDL C与TG水平有明显上升。与美国 90年代的资料相比 ,TC低 0 4 1(男 )mmol/L及0 4 7(女 )mmol/L ,LDL C低 0 5 2 (男 )mmol/L及 0 39(女 )mmol/L ,HDL C显著高于美国人。　结论　与 80年代相比血脂的性别差异与增龄变化规律不变。北京部分人群血脂LDL C上升主要在 80年代后期 ,90年代稳定而略有下降。TG升高幅度较大 。Objective To study the serum lipid levels and the prevalence of lipid abnormalities in the population of Beijing civil servants during 2001 2002, and to examine the changing trends of lipid levels by comparing the data with that of a similar study during 1984 1986. Methods A total of 31 068 subjects including government employees, medical and educational workers and scientific research personnel (male:female 6:4) were studied. Their health behavior and medical history were taken by questionnaires. All participants had a physical examination and blood chemistry tests. Blood lipid including total cholesterol (TC), low density lipoprotein cholesterol (LDL C), high density lipoprotein cholesterol (HDL C) and triglyceride (TG) were analyzed. Results TC, LDL C and TG levels were increased significantly as compared with the previous study during 1984 1986, but the variation of lipid levels with age and sex differences were remain unchanged. Age adjusted prevalence of dyslipidemia and its distribution in different sexes and age groups were statistically analyzed. Comparing the results with the data of the United States of America in 90 th , TC level was lower by 0 41 mmol/L in men and 0 47 mmol/L in women whereas LDL C level was lower by 0 52 mmol/L in men and 0 39 mmol/L in women. HDL C was significantly higher than that of the United States of America in both sexes. Conclusions The mean levels of LDL C increased rapidly in late 80s and stabilized and descended slightly in 90s of the 20 th century. At present, the lipid level in Chinese is significantly lower than that in Americans.

关 键 词：血脂异常 增龄变化 LDL-C 流行率 职业人群 HDL-C TC 年代 性别差异 结论 

分 类 号：R446.1[医药卫生—诊断学]