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机构地区:[1]海第二医科大学附属新华医院血液科,上海200092
出 处:《临床血液学杂志》2004年第6期319-320,共2页Journal of Clinical Hematology
摘 要:目的 :了解恶性血液病患者的心理状况及治疗方法。方法 :在常规化疗前后 (相隔 6周 )用焦虑自评量表 (SDS)、抑郁自评量表 (SAS)各对患者测定 1次 ,期间进行一般性心理疏导 ,少数患者给盐酸氟西汀和氯硝西泮口服。另设对照组和正常人群组予以对照。结果 :研究组和对照组的SDS标准分均值为 4 6 .12± 11.6 1和4 5 .4 1± 13.5 2 ,均高于正常人群组 39.0 2± 9.89(均P <0 .0 1)。SAS的标准分均值为 4 7.78± 12 .17、4 7.0 9±13.89,均高于正常人群组 38.16± 9.92 (均 P <0 .0 1)。治疗后研究组和对照组的SDS分别为 31.2 3± 9.98和4 3.5 6± 10 .2 6 ,SAS分别为 37.18± 10 .81和 4 4 .94± 11.0 4 ,两组差异有统计学意义 (P <0 .0 1)。与治疗前相比 ,研究组有显著改善 (P<0 .0 1) ,而对照组改善不明显 (P >0 .0 5 )。盐酸氟西汀和氯硝西泮配合治疗SDS标准分大于 5 0分的患者 9例 ,标准分均值由 6 0 .5 6± 12 .31下降到 4 0 .12± 10 .76 (P <0 .0 1) ,6例患者分值降至 5 0分以下 ,下降 6 6 .7%。SAS大于 5 0分的有 10例 ,治疗后均值由 6 3.36± 11.4 2下降到 4 1.89± 10 .2 4 (P <0 .0 1) ,7例患者分值降至 5 0分以下 ,下降 70 .0 %。结论 :恶性血液病患者大部分存在焦虑、抑郁情绪 ,常规化疗下心理?Objective:To study the mental health of patients with malignant hematological diseases and assess the effect of general psychotherapy for anxiety and depression.Method:SAS and SDS were applied to inpatients with malignant hematological diseases (62 cases) and healthy people (30 cases). Patients were randomly assigned to two groups. One was treated with chemotherapy together with psychological intervention. The other as control with chemotherapy only. SAS and SDS were applied to patients after 6 weeks.Result:There were more mental health problems in patients with malignant hematological diseases than that in healthy controls. The experiment group had less anxiety and less depression after treatment compared with control group.Conclusion:Patients with malignant hematological diseases had more psychiatric symptoms and poorer mental health. Psychological intervention can improve the mental state of patients.
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