高血压病史与脑血管功能积分关系的分析  

The relationship between hypertension and cerebral hemodynamic scores of vascular function accumulative

作　　者：黄久仪[1] 王桂清[1] 曹奕丰[1] 沈凤英[1] 杨永举[1] 王艳[1] 

机构地区：[1]上海市脑血管病防治研究所,201318

出　　处：《中华流行病学杂志》2004年第11期989-991,共3页Chinese Journal of Epidemiology

基　　金：上海市科技发展基金(934113060;944912014)

摘　　要：目的 分析高血压病史与血压水平,探讨高血压病与脑血管功能积分的关系。方法 以队列人群中基线调查的高血压病史、血压水平和脑血管血液动力学指标检测值为基础数据,选择符合纳入标准的18512例为研究对象,以统一的方法计算脑血管功能积分,以年龄、高血压病年数和血压水平进行分组,比较高血压病患病与否、不同患病年数及不同血压水平等不同组间脑血管功能积分值的差异。结果 各年龄段高血压病组的脑血管功能积分值显著低于血压正常组,降低幅度为13.3分。在有高血压病史前5年内,随着患病年数增加,脑血管功能积分显著下降。随着血压水平上升,脑血管功能积分值呈明显下降趋势,当收缩压上升至140mm Hg或舒张压上升至95mm Hg时,脑血管功能积分低于75分。结论 高血压病史、高血压病患病年数及血压水平与脑血管功能积分降低均有显著关系。Objective To probe into the relationship between hypertension and hemodynamic score of cerebral vascular accumulative function by though studying the history of hypertension and level of blood pressure. Methods The database of blood pressure and cerebral vascular hemodynamic indexes(CVHI) were from baseline data and measurement in a cohort. 18512 participants who met the included criteria were enlisted in the study. The function scores were estimated using uniform methods according to CVHI. Participants were grouped by age, years of having hypertension and level of blood pressure. Differences of the function score between different groups were compared. Results The function score in hypertension group was significantly lower than that of normal tension group, which decreased by 13.3 points. Within 5 years of hypertension history, the function score decreased as course of hypertension prolonged. The same trend was found between the score and level of both systolic and diastolic blood pressure. When systolic blood pressure elevated to 140 mm Hg or diastolic blood pressure elevated to 95 mm Hg, the function score was below 75 points. Conclusion There were siginfieant relationship between decrease of the function scores and medical history, course of hypertension as well as level of blood pressure.

关 键 词：脑血管功能 血压水平 高血压病史 队列人群 血压正常 纳入标准 基线调查 分值 积分 患病 

分 类 号：R544.1[医药卫生—心血管疾病] R743[医药卫生—内科学]