颅脑损伤患者血浆D-二聚体含量与伤情严重程度及预后关系的研究  

Study on relationship between level of plasma D-dimer and severity as well as prognosis in patients with head injuries

作　　者：黄波[1] 伍爱平[1] 陈冬妹[1] 刘勇[1] 李政[1] 高添喜[1] 黄惠伦[1] 

机构地区：[1]中山市博爱医院,广东中山528403

出　　处：《医师进修杂志（外科版）》2004年第11期18-19,共2页

摘　　要：目的　探讨D -二聚体 (DD)含量与颅脑损伤病人伤情、预后的相关性。方法　应用DD定量测定的方法 ,动态检测 90例不同伤情的颅脑损伤病人血浆中DD的含量 ,探讨DD含量与格拉斯哥昏迷分级 (GCS)、格拉斯哥预后分级 (GOS)的关系。结果　患者组DD含量明显高于对照组 ;DD含量与GCS、GOS呈负相关 ,并随伤情演变同步升降。结论　血浆DD的定量测定有助于早期。Objective To study the correlation between levels of plasma D-dimer(DD)and the severity as well as prognosis of head injury.Methods The levels of plasma DD were quantitatively dynamic measured in 90 patients with head injuries. The relationship between Glasgow coma score(GCS),Glasgow outcome score(GOS) and the concentration of DD were studied.Results The levels of plasma DD in patients with head injuries was significantly higher than that of control group.The concentration of DD correlated negatively with GCS and GOS, which changed along with the condition of head injury.Conclusion The level of plasma DD may be useful for judging the severity and prognosis in the early stage of head injury.

关 键 词：D—二聚体 脑损伤 

分 类 号：R651.1[医药卫生—外科学]