人体蠕形螨感染的皮肤组织病理学观察  

Skin Histopathological Observations of Human Demodicidosis

作　　者：余礼军[1] 郭鄂平[2] 

机构地区：[1]十堰市中医院病理科,湖北十堰442012 [2]郧阳医学院寄生虫学教研室

出　　处：《医学动物防制》2004年第10期593-594,共2页Journal of Medical Pest Control

摘　　要：目的:观察人体蠕形螨感染所致皮肤组织病理学改变。方法:收集7例面部皮肤标本经HE染色后在显微镜下观察。结果:在患者面部皮损处扩大的毛囊和增生的皮脂腺中检查出大量蠕形螨成虫、若虫和虫卵。人体毛囊蠕形螨多寄生于毛囊的根部或毛囊周围组织内,被寄生的毛囊均有不同程度的扩张,虫体周围常可见淋巴细胞为主的慢性炎症细胞浸润,毛根角质化较常见。人体皮脂蠕形螨寄生部位为皮脂腺体及导管部,可见腺细胞增生而失去正常结构,但较少有炎症细胞浸润,导管部有轻度扩张。结论:人体蠕形螨寄生与皮肤组织病理学改变有密切关系。Objective:To observe the histopathological changes of the skin tissue which the human follicle mites infect. Methods: Seven biopsy materials of the face skin were collected and observed by HE dyeing under light microscope. Results: A number of the imagines, nymphs and eggs of human follicle mites were found in the dilated hair follicles injured skin of the patient's feature and the hyperplastic sebaceous glands. Mites parasitized in the dilated hair follicles or hy-perplastic sebaceous glands. Sometimes mites could be found in the external of hair follicle. The normal structure of hair root disappeared and became keratinization. Part of hair follicles enlarged like cylinder or cyst. The inflammatory cells were usually observed around the mites. Conclu-sionThe results showed that the histopathological changes were intimately in correlation with the infection of two species of human follicle mites and suggested that these mites were pathogenic in some skin diseases.

关 键 词：皮肤组织病理 人体蠕形螨感染 观察 增生 皮脂腺 改变 毛囊 寄生部位 若虫 虫体 

分 类 号：R758.56[医药卫生—皮肤病学与性病学] R757.3[医药卫生—临床医学]