安徽省医院感染监控网医院感染病原菌分布及耐药性分析  

Distribution and Antibacterial Resistance of Nosocomial Infection Pathogens from Provincial Nosocomial Infection Surveillance System(PNISS)

作　　者：杨琍琦[1] 童立慈[1] 何源沁[1] 

机构地区：[1]安徽医科大学附属医院,安徽合肥230022

出　　处：《中华医院感染学杂志》2004年第2期209-211,共3页Chinese Journal of Nosocomiology

摘　　要：目的　了解医院感染病原菌的分布及细菌的耐药情况。方法　对全省医院感染监控网 4 0所医院感染病原菌来源及细菌耐药进行统计分析。结果　在 84 90例医院感染病例中分离出病原菌 380 8株 (45 30 % ) ;病原菌以革兰阴性菌为主 ,占 4 2 33% ,主要来源于下呼吸道 ,占 38 81% ;大肠埃希菌对庆大霉素耐药率 6 7 93% ,与阿米卡星相比 ,对两者耐药性差异有显著性 (P <0 0 1) ,耐甲氧西林葡萄球菌为 6 6 89% ,分离出的病原菌对氨苄西林的耐药率均 >6 0 % ,大多数病原菌对常用抗菌药物均有较高的耐药率。结论　医院感染细菌的耐药性日趋严重 ,应引起高度重视。OBJECTIVE To investigate the distribution and drug resistance of nosocomial infection pathogens. METHODS Statistical methods were used to analyse the data of pathogen's origin and drug resistance from 40 hospitals of PNISS. RESULTS A total of 3 808 strains were isolated from 8 490 nosocomial infection cases (45.30%), from which the Gram-negative bacilli were predominate(42.33%). The pathogens were principally isolated from under respiratory tract (38.81%). The rate of gentamicin-resistant Escherichia coli was 67.93%, as compared with amikacin, the difference between them were significant. The rate of meticillin-resistant staphylococcus was 66.89%. Isolated pathogens were all resistant to ampicillin, the rates of drug resistance were over 60%. Pathogens were showed high drug resistance to common antibiotics. CONCLUSIONS The emergence of drug-resistant pathogens will continue to be a serious problem, we must take it intimately.

关 键 词：医院感染 病原体 分布 耐药性 

分 类 号：R181.32[医药卫生—流行病学]