哌拉西林/他唑巴坦在治疗腹腔重症感染中的应用  

Efficacy of Piperacillin/tazobactam Used to Treat Severe Intrabdominal Infection

作　　者：孙元水[1] 施敦[1] 张静霞[1] 邵钦树[1] 袁宏均[1] 

机构地区：[1]浙江省人民医院,浙江杭州310014

出　　处：《中华医院感染学杂志》2004年第2期215-216,共2页Chinese Journal of Nosocomiology

摘　　要：目的　评价哌拉西林 /他唑巴坦治疗腹腔重症感染的安全性和有效性。方法　对 2 7例因各种腹部病变继发重症腹腔感染患者采用哌拉西林 /他唑巴坦治疗 ,静滴剂量为每次 4 5g ,q8h～q12h ,疗程 5～ 10d。结果　临床治疗总有效率为 81 4 8% ,细菌总清除率为 84 85 % ,不良反应率 3 70 %。结论　哌拉西林 /他唑巴坦具有安全、低毒、抗菌谱广的特点 ,在腹腔重症感染治疗中值得推荐使用。OBJECTIVE To evaluate the clinical efficacy and safety in treating severe intrabdominal infection with piperacillin/tazobactam. METHODS Twenty - seven patients with severe intrabdominal infection after abdominal disease were treated with piperacillin/tazobactam 4.5g,iv drip q8h-q12h for 5-10d. RESULTS The total effective rate was 81.48%. The killing rate of bacteria was 84.85% and side effect rate was 3.70%. CONCLUSIONS Piperacillin/tazobactam is worth recommending to use in patients with severe intrabdominal infection.

关 键 词：哌拉西林/他唑巴坦 腹腔感染 疗效 

分 类 号：R978.1[医药卫生—药品]