超声技术评价老年心血管病患者颈动脉粥样硬化的临床意义  

Vascular Ultrasonic Evaluation of Peripheral Atherosclerosis in Elderly Patients with Cardiovascular Disease

作　　者：刘芳[1] 欧阳福珍[1] 赵玮[1] 宋以信[1] 祁芸云[1] 

机构地区：[1]北京大学第一医院老年病内科,北京市100034

出　　处：《中国超声医学杂志》2004年第11期831-834,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的　评价超声技术用于检测老年心血管病患者颈动脉粥样硬化的临床意义。方法　应用二维和多普勒血管超声技术分别检测了 36例老年心血管病患者和 1 5例非心血管病患者颈动脉内膜 -中层厚度(IMT)、斑块总积分、斑块总面积及脑血流量。 36例老年心血管病患者又根据是否合并脑血管疾病分为 A组 (1 7例 ,合并脑血管疾病 )和 B组 (1 9例 ,无脑血管疾病 )。结果　二维超声显示心血管病组患者颈动脉 IMT、斑块总积分及斑块总面积均明显高于对照组 (P<0 .0 5 ) ;IMT与收缩压呈显著正相关 (r=0 .4 3,P<0 .0 5 ) ;斑块总积分及斑块总面积与冠脉病变支数之间呈显著正相关 (相关系数分别为 0 .35、 0 .5 1 ,P<0 .0 5 ) ;心血管病组患者颈总动脉、颈内动脉及椎动脉狭窄程度显著高于对照组 (P<0 .0 5 )。多普勒超声显示心血管病组中 A组患者颈总动脉、颈内动脉、椎动脉血流量及脑血流量均显著低于 B组及对照组 (P<0 .0 5 ) ,脑血流量与脑血管疾病的发生显著负相关 (r=- 0 .5 8,P<0 .0 5 )。结论　应用综合血管超声技术检测老年心血管病患者颈动脉粥样硬化有助于了解疾病的不同状态 ,便于判断病程及预后 ,对临床工作具有很大的指导意义。Objective To evaluate the clinical significance of peripheral atherosclerosis in elderly patients with cardiovascular diseases using vascular ultrasound.Methods Carotid intima-media thickness(IMT),total plaque score,plaque area and cerebral blood flow were measured by vascular ultrasound in 36 elderly patients with cardiovascular diseases and 15 without cardiovascular diseases(the control).The 36 elderly patients with cardiovascular diseases were divided into two groups:group A(17 cases,with cerebrovascular diseases) and group B(19 cases,without).Results Carotid IMT、total plaque score and plaque area were higher in elderly patients with cardiovascular diseases than those of the control( P <0 05) IMT was related to systolic pressure( r =0 43, P <0 05) Total plaque score and plaque area were related markedly to the numbers of culprit coronary arteries( P <0 05) The stenosis degrees of the common carotid artery,internal carotid artery and vertebral artery in the patients with cardiovascular diseases were more severe than those of the control( P <0 05) Doppler imaging showed that the blood flow of the common carotid,internal carotid ,vertebral and cerebral arteries in group A were decreased than in group B and in the control( P <0 05) There was negative correlation between the total cerebral blood flow and occurrence of cerebral vascular disease( r =-0 58, P <0 05 ) Conclusions The detection of peripheral atherosclerosis in elderly patients with cardiovascular diseases by vascular ultrasound was helpful for understanding the course and prognosis of cardiovascular diseases,which was significant in the clinical.

关 键 词：心血管病 患者 脑血管疾病 老年 颈动脉粥样硬化 IMT 对照组 面积 结论 合并 

分 类 号：R445.1[医药卫生—影像医学与核医学]