类风湿关节炎表皮生长因子及β_2微球蛋白的测定  

Determine of Epidermal Growth Factor and β_2-Microglobulin in Patients with Rheumatoid Arthritis

作　　者：林星[1] 郑斌生[1] 林玲[1] 杨萍[1] 陈平[1] 陈健[1] 

机构地区：[1]福建医科大学福清教学医院,福建福清350300

出　　处：《现代诊断与治疗》2004年第6期327-328,共2页Modern Diagnosis and Treatment

基　　金：福建省福清市科技发展基金资助

摘　　要：目的　探讨表皮生长因子 (EGF)与 β2 微球蛋白 ( β2 M )在类风湿关节炎 (RA)发病机理及诊断中的意义。方法　用放射免疫分析法 (RIA)测定 71例RA患者血清EGF、β2 M。结果　RA患者血清EGF、β2 M显著升高 ,说明EGF、β2 M在RA的发病中可能起一定作用 ,但与RA的活动性无关。Objective To investigate the roles of epidermal growth factor(EGF) and β_2-microglobulin(β_2-M) in the pathogenesis and diagnosis of rheumatoid arthritis(RA).Method 71 patients with RA were observed.EGF and β_2-M in serum were measured by radioimmunoassay.Results The levels of EGF and β_2-M in serum of patients with RA were significantly higher than those of the controls.Conclusions EGF and β_2-M may play a role in the pathogenesis of RA,but they aren't related to the activity of RA.

关 键 词：RA β2—M Β2微球蛋白 类风湿关节炎 EGF 表皮生长因子 患者 活动性 

分 类 号：R593.22[医药卫生—内科学] R644[医药卫生—临床医学]