不同针法对急性佐剂性关节炎大鼠下丘脑β-内啡肽的后效应观察  

Investigation on post-effects of different needling methods on β-endorphin in the hypothalamus in the rat of acute adjuvant arthritis

作　　者：梁繁荣[1] 刘雨星[1] 罗荣[1] 赵纪岚[1] 余曙光[1] 夏晓红[1] 陈瑾[1] 

机构地区：[1]成都中医药大学针灸推拿学院,四川610075

出　　处：《中国针灸》2004年第11期782-784,共3页Chinese Acupuncture & Moxibustion

基　　金：四川省教育厅资助

摘　　要：目的 :探求不同针法镇痛后效应的下丘脑作用机制。方法 :以急性佐剂性关节炎 (AA)大鼠为疼痛模型 ,比较手针组、穴注组、电针组和刺血组AA大鼠下丘脑 β 内啡肽 (β EP)的含量。结果 :不同针法治疗后 ,在 0 5h内 ,都使 β EP的含量进一步升高 ,其中电针组和手针组的效应持续到 30min。结论 :不同的针法产生的效应不同 ,以手针法效果最优。Objective To study on hypothalamic mechanisms of an al gesic post-effects of different needling methods. Methods β- endorphin contents in hypothalamus of the rat with acute adjuvant arthritis (AA) were compared among hand acupuncture group, acupoint-injection group, electroa cupuncture group and pricking blood group. Results After treatm ent with different needling methods, β-endorphin contents increased further wi thin 0.5 hour, the effects of the electroacupuncture group and the hand acupunct ure group lasting till 30 min. Conclusion Different needling me thods have different analgesic effects, the effect of hand acupuncture being the best.

关 键 词：针法 下丘脑 大鼠 手针 佐剂性关节炎 Β-内啡肽 急性 AA 

分 类 号：R245[医药卫生—针灸推拿学] R274[医药卫生—中医临床基础]