78例真菌二重感染的诱发原因分析  

An Analysis of the Inducement of Fungi Super infection in 78 Cases

作　　者：殷秀贞[1] 姜思通[1] 刘月芬[1] 刘雅莉[1] 

机构地区：[1]青岛大学医学院附属医院,青岛266003

出　　处：《药物流行病学杂志》2004年第6期335-337,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：目的 :对真菌二重感染病例诱发原因进行调查分析 ,以利于合理用药。方法 :采用时间段内全方位调查方法 ,对确认的 78例二重感染病例等项目的基础疾病、感染细菌及耐药情况、抗菌药应用情况进行统计分析。结果 :78例调查病例中 ,具有严重基础疾病 74例 (94 .87% ) ;培养出细菌 77株 ,其中广泛耐药 5 3株 (6 8.83% ) ;二重感染发生前抗菌药应用 2 6种 ,每例平均用药 14 .1d ,5 .2个品种 ,高效抗生素为用药主要品种。结论 :控制院内感染和加强合理用药是减少二重感染的重要举措。Objective: To analyze the inducement of the super infection for rational use of medicine.Method: 78 patients with super infection were investigated, including their original diseases, infected bacteria, its drug resistance, and the situation of their antibiotics application.Result: 74 patients ( 94.87% ) had severe original diseases; 77 strains of bacteria were incubated, and 53 strains ( 68.53% ) presented multiple resistance. Before the super infection occurred, 26 kinds of antibiotics were used, and 5.2 kinds were administered in one patient for 14.1 days. The major agents were higher performance antibiotics.Conclusion: Two important measures to reduce super infection are to control infection in hospital and enhance rational drug use.

关 键 词：真菌 二重感染 诱发原因 细菌耐药性 抗菌药 

分 类 号：R969.3[医药卫生—药理学]