甲状旁腺功能亢进^(99m)Tc-MIBI/^(99m)TcO_4^-显像的临床价值  

Clinical value of ^(99m)Tc-MIBI/^(99m)TcO_ 4^- substraction imaging in hyperparathyroidism

作　　者：陈维安[1] 崔颖鹏[2] 李春亿[1] 梁宏[1] 胡平[1] 

机构地区：[1]中山大学附属第一医院影像医学部核医学科,广州市510080 [2]中山大学附属第一医院检验医学部,广州市510080

出　　处：《实用医学杂志》2004年第11期1240-1241,共2页The Journal of Practical Medicine

摘　　要：目的 :评价甲状旁腺功能亢进症 (甲旁亢 ) 99mTc MIBI/99mTcO4-显像的临床价值 ,并与B超和CT比较。方法 :2 2例拟诊甲旁亢患者进行了核素显像 ,显像资料均参照临床最终诊断结果进行了评价 ,并与同期的B超 (2 2例 )或CT检查 (12例 )进行对比分析。结果 :2 2例患者中 ,18例确诊为甲旁亢 ,其中甲状旁腺瘤 16例 ,甲状旁腺增生2例。99mTc MIBI/99mTcO4-减影法、B超、CT的灵敏度分别为 88 9%、77 8%、80 %。特异性均为 10 0 % ,准确性为90 9%、81 8%、77 8%。99mTc MIBI/99mTcO4-减影法显像较B超和CT具有更高的诊断价值。结论 :99mTc MIBI/99mTcO4-显像对功能亢进的甲状旁腺有较好的诊断价值 。Objective To evaluate the clinical v al ue of 99mTc-MIBI/ 99mTcO 4- substraction imaging in hyperparat hyroidism and compare with ultrasound or CT.Methods 22 patients with highly suspectable hyperparathyroidi sm had been undergone 99mTc-MIBI/ 99mTcO 4- substraction imag ing. All material were evaluated according to final results and compared with u ltrasound (22 cases) or CT(12 cases).Results In 22 patients, 18 hyperparathyroidism were proven, i ncluding 16 adenomas、 2 hyperplasia. The sensitivity of 99mTc-MIBI/ 99mTcO 4- substraction imaging、 ultrasound、 CT were 88.9%, 77.8%, 8 0%, respectively. The specificity of 3 imaging was 100%. The accuracy of 99mTc-MIBI/ 99mTcO 4-、 ultrasound、 CT were 90.9%, 88.9%, 77.8%, respectively. The results showed that 99mTc-MIBI/ 99mTcO 4- wa s superior to ultrasound or CT. Conclusion 99mTc-MIBI/ 99mTcO 4- imaging c ould accurally diagnose hyperparathyroidism. It is a important location method o f preopreation.

关 键 词：甲状旁腺功能亢进症 ^99MTC-MIBI ^99mTcO4^-1 PTH 诊断 

分 类 号：R582.1[医药卫生—内分泌]