介入治疗移植肾动脉狭窄的疗效观察  

The Efficacy of Interventional Treatment for Transplant Renal Artery Stenosis

作　　者：梅雀林[1] 李彦豪[1] 何晓峰[1] 陈勇 卢伟[1] 曾庆乐[1] 赵剑波[1] 

机构地区：[1]第一军医大学附属南方医院介入科,广州510515

出　　处：《临床放射学杂志》2004年第11期989-991,共3页Journal of Clinical Radiology

摘　　要：目的　评价介入治疗移植肾动脉狭窄 (TRAS)的疗效。资料与方法　 2 0 0 0年 1月～ 2 0 0 2年 11月 ,采用经皮血管内成形术 (PTA)和 /或内支架治疗 2 0例TRAS患者 ,其中PTA治疗 14例次 ,内支架治疗 9例次。对治疗前后的血压、降压药物和血肌酐进行随访。结果　采用PTA治疗者 ,收缩压、舒张压、降压药物和血肌酐由术前的(15 7± 17)mmHg、(97± 7)mmHg、(1.5± 1.0 )种、(5 12± 2 96 ) μmol/L ,术后 1周降为 (137± 11)mmHg(P <0 .0 5 )、(86± 7)mmHg(P <0 .0 1)、(0 .9± 1.0 )种 (P >0 .0 5 )、(2 76± 2 2 6 ) μmol/L(P <0 .0 5 ) ,术后 6个月降为 (12 8±10 )mmHg(P <0 .0 1)、(83± 7)mmHg(P <0 .0 1)、(0 .8± 0 .9)种 (P >0 .0 5 )、(14 5± 5 5 ) μmol/L(P <0 .0 1)。采用内支架治疗者 ,收缩压、舒张压、降压药物和血肌酐由术前的 (15 4± 31)mmHg、(93± 12 )mmHg、(1.6± 1.0 )种、(338±14 2 ) μmol/L ,术后 1周降为 (134± 17)mmHg(P >0 .0 5 )、(82± 7)mmHg(P <0 .0 5 )、(0 .8± 1.0 )种 (P >0 .0 5 )、(197±76 ) μmol/L(P <0 .0 5 ) ,术后 6个月为 (132± 9)mmHg(P >0 .0 5 )、(83± 4 )mmHg(P <0 .0 5 )、(0 .5± 0 .8)种 (P >0 .0 5 )、(2 0 4± 16 9) μmol/L(P <0 .0 5 )。Objective To evaluate the efficacy of interventional treatment for transplant renal artery stenosis (TRAS).Materials and Methods From January 2000 to November 2002, 20 patients with TRAS were treated with interventional therapy, including 14 attempts of percutaneous transluminal angioplasty (PTA) and 9 attempts of stenting. The blood pressure, mumber of hypotensor and serum creatinine were followed before and after interventional therapy.Results (1)In PTA group, the mean systolic blood pressure, diastolic blood pressure, munber of hypotensor and serum creatinine level respectively decreased from a pre-PTA value of (157±17) mmHg, (97±7) mmHg, (1.5±1.0), (512±296) μmol/L to a 1-week post-PTA value of (137± 11) mmHg (P<0.05), (86±7) mmHg (P<0.01), (0.9±1.0) (P>05), (276±226) μmol/L (P<0.05), and to a 6-month later post PTA value of (128±10) mmHg (P<0.01), (83±7) mmHg (P<0.01), (0.8±0.9) (P>05), (145±55) μmol/L (P<0.01). In stent group, the mean systolic blood pressure, diastolic blood pressure, number of hypotensor and serum creatinine level respectively dropped from (154±31) mmHg, (93±12) mmHg, (1.6±1.0), (338± 142) μmol/L to (134±17) mmHg (P>0.05), (82±7) mmHg (P<0.05), (0.8±1.0) (P>05), (197±76) μmol/L (P<0.05) at 1 week later poststent, and (132±9) mmHg (P>05), (83±4) mmHg (P<0.05), (0.5±0.8) (P>0.05), (204± 169) μmol/L (P< 0.05) at 6 months later post stent. The total effectiverate was 81.8%.Conclusion Both PTA and stent implantation are effective therapeutic procedures for TRAS.

关 键 词：介入治疗 移植肾动脉狭窄 疗效观察 血管成形术 

分 类 号：R699.2[医药卫生—泌尿科学]