PLGA/TCP 材料的浓度-粘度性能研究  

Research on Concentration-Viscosity of PLGA/TCP for Bone Tissue Engineering

作　　者：向虎[1] 费小琛[1] 卢清萍[1] 颜永年[1] 熊卓[1] 林峰[1] 尹曦[1] 

机构地区：[1]清华大学机械工程系,北京100084

出　　处：《材料导报》2004年第7期93-95,共3页Materials Reports

基　　金：清华大学基础研究基金(重点):JZ2002001

摘　　要：为研究骨组织工程材料的成形性能。基于低温沉积制造工艺,研究了 PLGA/TCP 配制成浆料的浓度、粘度对成形性的影响。首先测定了材料的粘度随浓度的变化关系,然后对不同浓度的材料进行成形,发现材料的粘度对宏观成形效果起着决定性的作用,同时浓度变化使试样的微观结构具有较大差异。因此,可以通过控制浓度即粘度来调整试样的宏观、微观成形效果。In order to make research on the forming property,the relations among temperature,viscosity andforming property of the composite of PLGA/TCP are discussed,based on the process of Low-temperature DepositionManfacturing(LDM).Firstly the relation between concentration and viscosity is studied.The materials of various con-centration are formed,through which it can be seen that the viscosity is the key factor for the macroscopical impres-sion,but microcosmic structures are quite different relative to the concentration.So,it is concluded that the macrocos-mic and microcosmic requirements can be satisfied by adjusting the concentration which can lead to necessary viscosi-ty.

关 键 词：粘度 浓度 PLGA/TCP 低温沉积制造 骨组织工程 

分 类 号：R318[医药卫生—生物医学工程]