肺癌介入治疗模拟实验系统  

A Simulating Experimental System for Interventional Treatment of Lung Cancer

作　　者：吴效明[1] 张士华[1] 岑人经[1] 袁支润[2] 袁华[2] 

机构地区：[1]华南理工大学生物力学研究所,广州510640 [2]四川大学生物力学研究所,成都610065

出　　处：《生物医学工程学杂志》2004年第4期640-644,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目 ( 19972 0 44 );广东省自然科学基金资助项目 ( 0 2 0 83 2 )

摘　　要：为了深入研究肺癌介入治疗的血流动力学机理 ,设计了肺癌介入治疗的模拟实验系统。这个系统可以在各种生理参数条件下模拟药物灌注的手术操作过程 ,测试灌注效果。允许调节的参数包括 :心输出量、主动脉血压、压力波形、脉动周期、支气管动脉流量以及选用不同型号的导管、采用不同的注射速度或注射方式等 ,小分支动脉的开口位置及管径也可以改变。文中给出了应用我们研究的 p H值测定法测定的自然灌注区基本形态。In order to go deeply into the researches on the theory of hemodynamics for interventional treatment of lung cancer,we have designed a simulating experimental system. Using the experimental system,we can simulate the operation process and test the effect of drug infusion under a variety of physiological parameters. The parameters that admit of adjustment are: cardiac output,blood pressure of aorta,waveform of pressure,puluse period,blood flow in bronchial artery and different types of catheter,injecting velocity,injecting technique,etc. In addition,the entrance position and blood vessel diameter of small embranchment artery can be changed. In this paper are presented the application of our pH-testing method to natural infusion region and the determined representational shape and size.

关 键 词：肺癌 介入治疗 模拟实验 血流动力学 药物灌注 

分 类 号：R734.2[医药卫生—肿瘤] R73-36[医药卫生—临床医学]