镇痛灵对四氧嘧啶糖尿病大鼠血糖水平的影响  

Effect of ZTL on blood glucose concentration in diabetes in rats induced by alloxan

作　　者：陶惠然[1] 张桂芳[1] 杨殿生[1] 张景祥[1] 刘金平[2] 赵智华[2] 陈美琳[3] 

机构地区：[1]佳木斯医学院生理教研室 [2]佳木斯医学院附属药厂 [3]佳木斯医学院药学系药理

出　　处：《佳木斯医学院学报》1993年第4期1-3,共3页

摘　　要：本研究观察了中药制剂镇痛灵及其组成药卷柏、木贼对四氧嘧啶糖尿病大鼠高血糖的影响。结果表明:腹腔注射镇痛灵(2.58/kg)后的3天、6天、9天及12天大鼠血糖与损伤对照组大鼠同天血糖相比显著降低(P<0.01),且该药的降糖作用存在着明显的剂量依赖关系。腹腔注射卷柏(12.5g/kg)后的3天、6天、9天的血糖值明显低于损伤对照组(P<0.01)。腹腔注射木贼(12.5g/kg)后大鼠血糖水平呈下降趋势,无统计学差异(P>0.05)。Effects of Zhen Tong Ling(ZTL),Selaginella Tamariscina spring(STS)and Equisetum Hienale L(EHL)on changes in blood glucose level were observed in alloxan—caused diabetic rats.The results demonstrated that blood glucose level was much lower after peritonitis injection of ZTL(25g/kg)and STS(12.5g/kg)at 3,6,9,12 days than that of the control group at the same time(P<0.01),with a dose—dependent relation,while there was no significant difference blood glucose following EHL injection compared with control group(P >0.05).

关 键 词：镇痛灵 四氧嘧啶 糖尿病 血糖 大鼠 

分 类 号：R977.15[医药卫生—药品]