The Etiology of Genital Ulcer Disease among Patients Attending Sexually Transmitted Disease Clinics in Guangzhou,China  

作　　者：谷进 曾志荣 陈荣章 朱慧兰 邱晓珊 

机构地区：[1]The Third Affiliated Hospital of SUMS [2]The First Affiliatedd Hospital of Sun Yat-sen university of medical science (SUMS) [3]Guangzhou Institute of Dermatology and Veneology

出　　处：《Chinese Journal of Sexually Transmitted Infections》2002年第2期29-31,共3页中华性传播感染杂志（英文版）

摘　　要：Objective: To investigate the etiology of genital ulcerdisease (GUD) among patients attending sexuallytransmitted disease (STD) clinics in Guangzhou, China. Methods: Between September 8, 1998, and August 9,2001, 267 patients with a genital ulcer were clinicallyassessed. Clinical etiology of GUD was dependent onphysical appearance and microbiologic examination,including the following: dark field microscopy and serologyfor Treponema pallidum (TP), swabs of genital ulcer forHerpes simplex virus (HSV), processed quantitativefluorescent polymerase chain reaction (QF-PCR) forsimultaneous detection of HSV, TP, Haemophilus ducreyi(HD), Human papillomavirus (HPV), and serology for HIVinfection. Results: Two hundred thirty men and thirty-sevenwomen with a median age of 33.4 (range 16-74 years) wereanalyzed. The etiology of GUD was syphilis (26.59%)(71/267), genital herpes (17.60%) (47/267), condylomataacuminata (4.87%) (13/267), candidiasis (3.37%) (9/267),bacterial infection (3.75%) (10/267), and multiple infection(6.74%) (18/267). The seroprevalence of HIV was 0.75%(2/267). No etiology was identified in 50.56% (135/267). Conclusion: The etiology of GUD among STD patients inour area was multifactorial with a predominance of syphilisand genital herpes. Based on this limited data obtained atSTD clinics, HIV infection was not common.

关 键 词：生殖器溃疡 GUD 性传播疾病 STD 临床研究 血清学检测 密螺旋体 单纯疱疹病毒 HSV 人乳头瘤病毒 HPV 发病机理 

分 类 号：R759[医药卫生—皮肤病学与性病学] R446.11[医药卫生—临床医学]