痂囊腔菌素A的溴代反应及产物的光敏活性研究  

The bromination of elsinochrome A and photosensitivity of its derivatives

作　　者：黄坤[1] 朱洪友[1] 李聪[1] 古昆[1] 陈远腾[1] 

机构地区：[1]云南大学应用化学系,云南昆明650091

出　　处：《云南大学学报（自然科学版）》2003年第4期352-354,共3页Journal of Yunnan University(Natural Sciences Edition)

基　　金：国家自然科学基金资助项目(20262007);云南省自然科学基金资助项目(2000C0106M).

摘　　要：研究了痂囊腔菌素A的溴代反应,反应得一溴代和二溴代2个产物.用微生物纸片法分别测定痂囊腔菌素A、一溴代和二溴代物的光敏活性.结果表明溴代产物的光敏活性均增强,尤其是二溴代物明显增强.The bromination of EA was studied.Two products,5(8)-Br-EA and 5,8-di-Br-EA were obtained. The photosensitivity of EA,5(8)-Br-EA, 5,8-di-Br-EA were tested by paper disk method in microbiology.The photosensitivity of the products,especially that of 5,8-di-Br-EA,was found to be higher than that of EA.

关 键 词：痂囊腔菌素A 溴代反应 光敏活性 微生物纸片法 溴代产物 二溴代物 EA 抑菌活性测试 

分 类 号：O625.46[理学—有机化学] O621.255.1[理学—化学]