Pharmacological Research of Tetrandrine and Fangchinoline, the Major Components of Stephania Tetrandrae  

作　　者：张永鹤 方莲花 库宝善 姚海燕 

机构地区：[1]DepartmentofPharmacology,SchoolofBasicMedicalSience,PekingUniversity,Beijing100083 [2]InstituteofMaterialMedica,PekingUnionMedicalCollege＆ChineseAcademyofMedicalSciences,Beijing100050

出　　处：《中国药理通讯》2004年第2期11-11,共1页

摘　　要：Purpose: The root of the Chinese herbal remedy Han Fang Ji ( Radix of Stephania Tetrandrae) has been used since antiquity by Chinese physicians as an ahtihypertenion, antirheumatic, analgesic and antipyretic agent. Tetrandrine (TET) and fangchinoline (FAN), the bisbenzylisoquinolide alkaloids, are the major components of Han Fang Ji. TET has been well known as a natural occurred non - specific calcium channel blocker. However, the effects of TET on the cardiovascular system are not fully understood, and that a few of researches about FAN, an another major constituent of Han Fang Ji, are reported. Thus, we have done these studies to investigate and compare the effects of TET and FAN on cardiovascular system,CNS and multi - drug resistance to anticancer drugs for several years.

关 键 词：药理学研究 防己醇灵 主要成分 斯蒂芬妮 含量检测 

分 类 号：R927.1[医药卫生—药学]