Toosendanin induced continuous increase in Ca^2＋ current in NG108-15 cells  

作　　者：Mu-FengLi Yu-LiangShi 

机构地区：[1]ShanghaiInstitutesforBiologicalSciences,ChineseAcademyofSciences,Shanghai200031

出　　处：《中国药理通讯》2004年第2期17-17,共1页

摘　　要：Toosendanin (TSN), a triterpenoid derivative from Chinese traditional medicine, is a selective presynaptic blocker and an effective antibotulismic agent. Recently, its apoptosis-initiated effect and cytotoxicity in several human cancer cell lines were observed. Since a transient increase in intracellular Ca^2+ concentration ([Ca^2+]i) triggers and facilitates

关 键 词：川栋素 组胺 NG108-15 细胞增殖 钙元素 大鼠 药理实验 

分 类 号：R965[医药卫生—药理学]