Different effects of valproate on methamphetamine-and cocaine-induced behavioral sensitization in mice  

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作  者:Jun-XuLi Jian-HuiLiang 

机构地区:[1]DepartmentofNeuropharmacology,NationalInstituteonDrugDependence,PekingUniversity,Beijing,100083

出  处:《中国药理通讯》2004年第2期44-45,共2页

摘  要:Multiple intermittent administration of psychostimulants induces a behavioral sensitization, which is characterized by the augmentation of locomotor activity and stereotyped behavior, even after their long-term withdrawal. This kind of behavioral effects is thought to serve as a useful animal model that mimics the behavioral responses in drug craving.

关 键 词:2-丙基戊酸钠 脱氧麻黄碱 可卡因 动作感受器 大鼠 

分 类 号:R971[医药卫生—药品] R965[医药卫生—药学]

 

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