Leukotriene receptor antagonist ONO-1078 attenuate N-metyl-D-aspartate - mediated neurotoxicity in rats  

作　　者：ZHANGLi-Hui WEIEr-Qing 

机构地区：[1]DepartmentofPharmacology,SchoolofMedicine,ZhejiangUniversity,Hangzhou310031

出　　处：《中国药理通讯》2004年第2期54-55,共2页

摘　　要：AIM: To investigate the possible effect of ONO-1078 t pranlukast, 4-oxo-8-[p-(4-phenylbutyloxy) benzoyl-amono]-2- (tetrazol-5-yl)-4H-1-benzopyran hemihydrate],a potent leukotriene receptor antagonist,on N-metyl-D-aspartate (NMDA)-mediated neurotoxicity in rats. METHODS: Brain injury was induced by NM-

关 键 词：细胞受体 ONO-1078 削弱作用 天门冬氨酸 神经毒性 大鼠 

分 类 号：R971[医药卫生—药品] R965[医药卫生—药学]