Studies of ATP sensitive potassium channels on 6 - hydroxydopamine and haloperidol rat models of Parkinson＇ s disease： Implications for treating Parkinson＇ s disease？  

作　　者：WANGSen YANGYong DINGJian-Hua HUGang 

机构地区：[1]DepartmentofPharmacologyandNeurobiology,NanjingMedicalUniversity,Nanjing210029,China

出　　处：《中国药理通讯》2004年第2期58-59,共2页

摘　　要：Parkinson' s disease is a common neurodegenerative movement disease that affects more than 1% of the elderly population, characterized by a preferential loss of the dopaminergic neurons of the substantia nigra pars compacta. Although during the past score, major biochemistry process such as mitochondrial dysfunction, oxidative stress and glutamate

关 键 词：帕金森病 ATP 钾通道 6-氧化多巴胺 氟哌啶醇 大鼠 药物实验 

分 类 号：R971.5[医药卫生—药品] R965[医药卫生—药学]