牛骨形成蛋白-多孔人造骨复合物的临床应用  

THE CLINICAL APPLICATION OF THE BOVINE BONE MORPHOGENETIC PROTEIN AND BIOMATERIAL BONE COMPLEX

作　　者：杨超[1] 葛宝丰[1] 苏增贵 白孟海[1] 曾述强[1] 

机构地区：[1]兰州军区总医院创伤外科研究所,730050

出　　处：《解放军医学杂志》1993年第1期42-43,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：1980年9月～1991年5月在动物实验的基础上,采用多孔人造骨(BB)材料、复合牛骨形成蛋白(bBMP)进行骨折与骨不连治疗,临床应用10例,术后早期出现骨愈合征象,临床检查及X线评价,9例治疗效果良好,无合并症发生。结果表明bBMp-多孔人造骨复合物在目前用量下是安全的、有效的骨诱导物质,能明显地促进骨愈合过程,可作为骨折治疗及骨不连治疗的一种新材料。10 nonunion and delayed-union fractures of long bones had been treated with the bovine bone morphogenetic protein (bBMP) and biomaterial bone (BB) composite implantation from Sept 1989 to May 1991. The signs of early bone healing appeared. Except one patient clinical result and roentgenographic assessment were good in all the cases. No complication was seen. Our result had showed that the bBMP-BB composite transplants were safe and efficacious, as it might promote healing of fractures.

关 键 词：骨形成蛋白 人造骨复合物 骨折 

分 类 号：R318.08[医药卫生—生物医学工程]