麻风无痛性神经炎早期发现的研究  

Early detection of silent neuritis in leprosy

作　　者：徐跃华 郭振东 钟定华 庄岳鑫 

机构地区：[1]广东省泗安医院,广州510500 [2]广东省东莞市慢性病防治院,523000 [3]广东省清远市皮肤病防治所,511515 [4]广东省潮州市慢性病防治站,521000

出　　处：《中国麻风皮肤病杂志》2004年第4期332-333,共2页China Journal of Leprosy and Skin Diseases

摘　　要：目的 :　了解麻风无痛性神经炎在各型及实施MDT治疗的不同时期的发生情况。方法 :　定时测试周围神经的感觉和运动功能 ,前后对照 ,以发现早期无痛性神经炎。结果 :　观察 4 5 6例MDT治疗期 ,监测期及解除监测期患者 ,发现无痛性神经炎 4 8例 ,累计检出率 10 .5 3%。治疗期患者的发生率明显高于监测期及解除监测期患者 (P <0 .0 1) ,尺神经和胫神经检出率明显高于其它神经 (P <0 .0 1)。结论 :定期检测周围神经功能 。Objective: To determine the incidence rate of silent neuritis in leprosy under MDT, post-MDT follow-up and released from control (RFC).Methods: The sensory and motor function of peripheral nerves at regular intervals was examined in three cohorts of leprosy patients.Results: Total 456 leprosy cases under MDT, post-MDT and RFC were recruited. During a maximum of 24 months 48 cases of silent neuritis were detected with an incidence rate 10.53%. The detection rate of cases under MDT was significantly higher than that in patients of post-MDT and RFC (P<0.01). The most common involved nerves were ulnar and tibial nerves. The detection rate for the two nerves was higher than that in other nerves (P<0.01). Conclusion: It is important that early detection of silent neuritis by examining function of peripheral nerve at regular intervals.

关 键 词：麻风 无痛性神经炎 早期诊断 并发症 

分 类 号：R755[医药卫生—皮肤病学与性病学] R745.1[医药卫生—临床医学]