荧光定量PCR检测女性商业性性工作者性传播感染  

Detection of sexually transmitted infections among detained female commercial sex workers by fluorescent quantitative PCR assay in Shenzhen.

作　　者：杨帆[1] 李永双[2] 周华[1] 吴志华[2] 

机构地区：[1]深圳市慢性病防治院皮肤病研究所,深圳518020 [2]广东医学院附属医院皮肤性病研究所

出　　处：《中国麻风皮肤病杂志》2004年第4期334-335,共2页China Journal of Leprosy and Skin Diseases

摘　　要：目的 :　了解女性商业性性工作者 (FSWs)沙眼衣原体 (Ct)、淋球菌 (NG)、单纯疱疹病毒 (HSV)及人乳头瘤病毒 (HPV)等常见性传播感染 (STI)的患病情况。方法 :　选取深圳市收容教育所 2 0 0 2年 11～12月因卖淫而收容教育的 130例FSWs作为研究对象 ,采用荧光定量PCR(FQ -PCR)检测宫颈分泌物Ct、NG、HSV及HPV感染。结果 :　FQ -PCR检测 130例FSWs宫颈分泌物的Ct阳性检出率为 32 .3%、NG阳性检出率为 16 .2 %、HSV为 5 .4 %、HPV6 11、HPV16和HPV18分别为 7.7%、2 3.8%和 12 .3%。STI总的阳性检出率为 6 0 .8% ,混合感染率为 2 5 .4 %。结论 :　女性商业性性工作者的STI患病率高 。Objective:To determine the prevalence of sexually transmitted infections (STI) among female commercial sex workers (FCSWs) in Shenzhen. Methods:Fluorescent quantitative PCR was used to detect major organisms of sexually transmitted infections among 130 detained FCSWs in a women's reeducation center in Shenzhen.Results:The prevalence rate of CT,NG,HSV,HPV6/11,HPV16 and HPV18 for cervix secretion is 32.3%,16.2%,5.4%,7.7%,23.8% and 12.3% respectively. The overall positivity rate of STIs was 60.8% (79/130), and the prevalence rate of mixed STIs was 25.4%. Conclusion:The prevalence of STI was high among FCSWs in Shenzhen.

关 键 词：荧光定量PCR 检测 女性商业性性工作者 性传播感染 沙眼衣原体 淋球菌 单纯疱疹病毒 人乳头瘤病毒 

分 类 号：R759[医药卫生—皮肤病学与性病学] R446.5[医药卫生—临床医学]