Characterization of the Interaction between Bovine Serum Albumin and Lomefloxacin by Capillary Zone Electrophoresis  

作　　者：MingGUO QingSenYU JianWeiYAN FeiTAN GuoZhengMA 

机构地区：[1]DepartmentofChemistry,ZhejiangUniversity,Hangzhou3100271 [2]DepartmentofChineseMedicineScience＆Engineering,ZhejiangUniversity,Hangzhou3100271

出　　处：《Chinese Chemical Letters》2004年第11期1331-1334,共4页中国化学快报（英文版）

摘　　要：Three capillary zone electrophoresis (CZE) methods of the frontal analysis (FA), vacancy peak (VP) and simplified Hummel-Dreyer (SHD) were applied to investigate interaction between bovine serum albumin (BSA) and lomefloxacin, the experimental condition was established after a large number of tests. Based on the site-binding model, the binding parameters were measured according to the site model by Scatchard.Three capillary zone electrophoresis (CZE) methods of the frontal analysis (FA), vacancy peak (VP) and simplified Hummel-Dreyer (SHD) were applied to investigate interaction between bovine serum albumin (BSA) and lomefloxacin, the experimental condition was established after a large number of tests. Based on the site-binding model, the binding parameters were measured according to the site model by Scatchard.

关 键 词：CZE the site model BSA lomefloxacin. 

分 类 号：Q512.1[生物学—生物化学]