降脂灵治疗高脂血症疗效和安全性的观察  

Efflcacy and safety of Jiangzhiling in treating hyperlipidemia

作　　者：安海梅[1] 秦彦文[1] 杜兰平[1] 潘晓冬[1] 王绿娅[1] 

机构地区：[1]首都医科大学附属北京安贞医院职工保健科,100029

出　　处：《中国药物与临床》2004年第11期842-843,共2页Chinese Remedies & Clinics

摘　　要：目的观察中药降脂灵片对高脂血症患者的降脂疗效及安全性。方法对入选的31例高脂血症患者,进行开放性研究,治疗前后自身对照;予降脂灵15片/d,分3次服用。为期4周,于实验前及实验结束后,检测血清总胆固醇、甘油三酯、肝肾功能、血清肌酸激酶等的变化。结果治疗后胆固醇水平与治疗前经较显著下降[(5.8±0.8)mmol/Lvs(6.3±0.7)mmol/L,P<0.05)];甘油三酯、肝肾功能、肌酸激酶变化无统计学意义(P>0.05)。结论中药降脂灵有一定的降低血清胆固醇作用,而对甘油三酯肝肾功能、血清肌酸激酶等无明显影响,是一种安全有效的降脂中药。Objective To evaluate the efficacy and safety of Jiangzhiling tablet in patients with hyperlipidemia. Methods Thirty-one patients with hyperlipidemia were treated with Jiangzhiling 15 pills a day, by three times for 4 weeks. Observations were made on the changes of total cholesterol (TC), triglycerides (TG), liver-kidney function, creatine kinase (CK) and others. Results TC levels decreased significantly after Jiangzhiling treatment (P<0.05). TG, CK, liver-kidney function had no obvious changes (P>05). Conclusion Jiangzhiling has the effect of improving blood lipid metabolism. It is an effective, safe drug in the treatment of hyperlipidemia.

关 键 词：降脂灵 高脂血症 安全性 中医药疗法 疗效观察 

分 类 号：R259[医药卫生—中西医结合]