背向散射积分对早期心肌缺血识别价值的实验研究  

Value of Integrated Backscatter Differentiating Early Phase of Myocardial Ischemia:An Experimental Study

作　　者：刘庆华[1] 赵宝珍[1] 王宝文[2] 倪文[3] 徐激斌[4] 郑建明[5] 张生明[5] 

机构地区：[1]解放军第二军医大学附属第一医院超声科,上海市200433 [2]解放军第59医院超声科 [3]解放军第二军医大学附属第一医院麻醉科,上海市200433 [4]解放军第二军医大学附属第一医院胸外科,上海市200433 [5]解放军第二军医大学附属第一医院病理科,上海市200433

出　　处：《中国超声医学杂志》2004年第6期411-413,共3页Chinese Journal of Ultrasound in Medicine

基　　金：上海市科学技术发展基金的资助 (No.0 1 4 1 1 90 98)

摘　　要：目的　探讨背向散射积分对早期心肌缺血的识别价值。方法　 10头正常猪 ,开胸后通过 Ameroid环套扎猪冠脉的左回旋支 (L CX) ,6例成功建立慢性心肌缺血模型 ,分别于术前、术后 2周、 5周乳头肌短轴切面测量左心室侧后壁的背向散射积分 (IBS)指标—背向散射积分周期变异幅度 (CVIB)和背向散射积分平均值 (AII) ,并与病理结果对照。结果　 AII值术后 2周、 5周与术前相比无显著差别 ,CVIB随时间总体变化趋势不明显 (P=0 .0 6 ) ,但术后 2周与术前相比CVIB值有所下降。结论　 CVIB和 AII能否识别极早期心肌缺血尚有待于进一步研究。Objective To assess the value of integrated backscatter differentiating early phase of myocardial ischemia.Methods The LCXs of coronary artery in 10 pigs were obstructed using Ameroid occlusions to make a hibernating myocardium model.Echocardiography was performed before,2 weeks or 5 weeks after operation and compared with histopathologic examination.The IBS indices(CVIB and AII) of posterior wall were obtained from short-axis view at papillary muscle level.Results Six of 10 pigs were made hibernating myocardium model successfully.The histopathologic examination mainly showed myocardium denaturation with a little necrosis.The IBS index,AII,showed no difference between those of the pre-operation and of the post-operation.Although the CVIB did not change significantly along the time,it was depressed at the 2nd week when compared with that of pre-operation.Conclusions It is uncertain whether CVIB and AII can distinguish the very early myocardial ischemia.Therefore,it is necessory that further research work should be launched.

关 键 词：背向散射积分 早期心肌缺血 术前 术后 实验研究 开胸 冠脉 结论 平均值 目的 

分 类 号：R445.1[医药卫生—影像医学与核医学]